Wham clusters all the applicant breakpoints and rounds their positions to the closest tenth foundation pair. The position with the very best read support is reported. In the event the tender-clipped consensus sequence is usually aligned to the putative breakpoint region utilizing the Smith-Waterman algorithm, the breakpoint is additional refined to
Wham is designed for paired-conclusion Illumina libraries with standard insert measurements (~300bp-500bp). Wham integrates mate-pair mapping, split browse mapping, comfortable-clipping, substitute alignment and consensus sequence dependent proof to predict SV breakpoints with solitary-nucleotide accuracy. Wham generates a blended pileup (catalog o
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